View source for Maximum likelihood

<font color="blue">Maximum de vraisemblance</font> (''Fr''). <font color="red">Maximale Wahrscheinlichkeit</font> (''Ge''). <font color="green">Máxima verosimilitud</font> (''Sp''). <Font color="black">Metodo della massima verosimiglianza</Font> (''It''). <Font color="purple">最尤法</Font> (''Ja'').


An approach to structure [[refinement]] in which the parameters of a structural model are modified to optimize the statistical probability of generating a set of observed intensities. The technique is often used in the refinement of structures of biological macromolecules, where the unfavourable parameter-to-observation ratio often leads to overfitted data and consequent systematic errors in least-squares minimization procedures.

[[Category:Biological crystallography]]
[[Category:Structure determination]]