Difference between revisions of "Isomorphous replacement"
From Online Dictionary of Crystallography
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A method of determining diffraction [[phase problem|phases]] from the differences in intensity between corresponding reflections from two or more [[isomorphous crystals]]. Most commonly used in the determination of protein structures, where it is possible to derive isomorphous crystals of native protein and of heavy-atom derivatives. | A method of determining diffraction [[phase problem|phases]] from the differences in intensity between corresponding reflections from two or more [[isomorphous crystals]]. Most commonly used in the determination of protein structures, where it is possible to derive isomorphous crystals of native protein and of heavy-atom derivatives. | ||
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== See also == | == See also == | ||
| − | * | + | *Chapter 2.3.3 of ''International Tables for Crystallography, Volume B'' |
| − | *''International Tables | + | *''International Tables for Crystallography, Volume F'' |
[[Category:Biological crystallography]] | [[Category:Biological crystallography]] | ||
[[Category:Structure determination]] | [[Category:Structure determination]] | ||
Revision as of 14:26, 15 May 2017
Substitution isomorphe (Fr). Isomorpher Ersatz (Ge). Substitución isomorfa (Sp). изоморфное замещение (Ru). Metodo della sostituzione isomorfa (It). 同型置換法 (Ja).
Definition
A method of determining diffraction phases from the differences in intensity between corresponding reflections from two or more isomorphous crystals. Most commonly used in the determination of protein structures, where it is possible to derive isomorphous crystals of native protein and of heavy-atom derivatives.
See also
- Chapter 2.3.3 of International Tables for Crystallography, Volume B
- International Tables for Crystallography, Volume F